Reverse Rett is a patient advocacy and research organisation focused on delivering treatments and a cure for Rett Syndrome to all those affected.
Rett Syndrome is a neurological condition which most often strikes previously healthy little girls between their first and second birthdays and leaves them with multiple disabilities and medical complexities for life.
Most people with Rett are unable to speak, walk or use their hands. Breathing problems, feeding tubes, seizures, anxiety, gastrointestinal and orthopedic issues are common.
Research has shown that girls with Rett do not have brain damage. They know and understand much more than their bodies allow them to show - but they are locked in, trapped by a body that cannot obey signals from their brain.
In 2007, with the successful reversal of Rett Syndrome in the lab, we entered a new era for research in which we knew a cure was possible. Over the last decade, we’ve invested in high quality research projects such as the RSRT gene therapy and Mecp2 Consortia which have delivered viable potential treatments to industry partners, for development into human clinical trials.
In 2021, these trials are firmly on the horizon and at Reverse Rett, we’re focused on doing what we need to do to build UK medical capacity to deliver complex emerging treatments for Rett Syndrome as soon as humanly possible.